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KMID : 0369819900200040209
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Jorunal of Korean Pharmaceutical Sciences
1990 Volume.20 No. 4 p.209 ~ p.215
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Efficacy Test of Commercial Digestives Containing Antacids , Digestive Enzymes and Herbal Drugs ( Ⅱ ) : Digestive Activity Test
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김종국/Kim CK
장정윤/나운용/ Jang JY/Lah WY
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Abstract
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The activities of s-amylase, α?amylase and protease of three combination products containing digestive enzymes, antacids and herbal drugs on the Korean market were estimated. The effects of antacids and herbal drugs on the activities of digestive enzymes were investigated. Starch-saccarifying activity of s-amylase, starch-dextrinizing activity of α?amylase and protein-peptic activity of protease were estimated by Somogy, Mc'Credy, and Casein-Folin method, respectivley. The optimal pH of s-amylase, α?amylase and protease were pH 5.0, 4.8 and 7.0, rcspectively. The digestive activities at optimal pH continued about eight hours. The digestive activities of individual enzymes were reduced to 40-90% by antacids and were affected somewhat positively or negatively by herbal drugs. Enzyme activities of the combination products were also affected by pH and reaction time.
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KEYWORD
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